A-PHP Pellets
€ 72,00 – € 604,00Price range: € 72,00 through € 604,00
Premium A-PHP Pellets from Nova Chemics – ultra-pure α-Pyrrolidinohexanophenone (>98% verified) in 15mg doses. Perfect for advanced analytical and forensic research. Buy A-PHP pellets online with fast, discreet worldwide shipping.
Buy A-PHP Pellets Online – Premium α-PHP (Alpha-PHP) 15mg Pellets for Research | Nova Chemics
When precision dosing is essential, researchers worldwide rely on Nova Chemics for the highest-quality A-PHP pellets available. Also known as α-Pyrrolidinohexanophenone or alpha-PHP, this potent synthetic cathinone is pressed into convenient 15mg pellets under pharmaceutical-grade conditions to ensure exceptional purity, uniformity, and batch-to-batch consistency. Every order includes a full certificate of analysis confirming purity above 98% through HPLC and GC-MS verification. As a leading supplier of research chemicals, Nova Chemics ensures our A-PHP pellets meet the demands of cutting-edge studies in neuropharmacology, toxicology, and forensic science. With its emergence as a key compound in the cathinone family since 2014, alpha-PHP has become indispensable for investigating novel psychoactive substances (NPS) and their impacts on monoamine systems, offering a pre-measured format that simplifies experimental workflows.
What Are A-PHP Pellets? Chemical Profile and Properties
A-PHP (α-Pyrrolidinohexanophenone, CAS 13415-86-6) belongs to the pyrrolidinophenone class of new psychoactive substances. With the molecular formula C₁₆H₂₃NO and molar mass of 245.37 g/mol, it features a hexanophenone backbone substituted with a pyrrolidine ring, providing enhanced lipophilicity and transporter selectivity compared to shorter-chain analogs like α-PVP. This structural extension—one additional methylene unit—yields distinct pharmacological nuances, making A-PHP pellets ideal for comparative SAR (structure-activity relationship) studies. First synthesized in the early 2010s, alpha-PHP was reported to the EMCDDA in 2014 as a designer drug analog, with its SMILES notation—CCCCC(C(=O)C1=CC=CC=C1)N2CCCC2—enabling precise computational modeling in QSAR analyses.
Recent stability assessments confirm A-PHP’s robustness in pellet form, with no degradation over 18 months under controlled conditions. The pressed pellets dissolve uniformly in assay buffers, ensuring accurate microdosing for in vitro applications. For researchers seeking reliable alpha-PHP 15mg pellets, Nova Chemics delivers lab-verified material free from contaminants, optimized for seamless integration into NDRI-focused protocols.
| Chemical Specifications for A-PHP Pellets | Details |
|---|---|
| IUPAC Name | 1-Phenyl-2-(pyrrolidin-1-yl)hexan-1-one |
| CAS Number | 13415-86-6 |
| Molecular Formula | C₁₆H₂₃NO |
| Molecular Weight | 245.37 g/mol |
| Purity (HPLC/GC-MS) | ≥98% (Nova Chemics Standard) |
| Pellet Dosage | 15mg per pellet (uniform compression) |
| Appearance | White to off-white solid pellets |
| Solubility | Soluble in ethanol (~20 mg/mL), DMSO (~10 mg/mL), methanol (~15 mg/mL), PBS pH 7.2 (~10 mg/mL) |
| Stability/Shelf Life | Up to 18 months at -20°C; stable in inert atmosphere |
| Melting Point | ~108.9°C (free base) |
| Storage Conditions | Cool, dry, dark place; airtight container with desiccant |
Why Researchers Choose Nova Chemics A-PHP Pellets
Scientists searching to buy A-PHP pellets online consistently select Nova Chemics because we deliver:
- Verified purity ≥98.5% (third-party tested via NMR, FTIR, and mass spectrometry)
- Pre-dosed 15mg pellets for effortless handling and reproducibility
- Complete analytical documentation with every shipment, including batch-specific CoA
- Competitive pricing on small packs and bulk A-PHP pellet orders, with tiered discounts for institutional buyers
- Fast, discreet EU-to-worldwide shipping, compliant with international NPS regulations
The pellet format eliminates weighing errors, crucial for sensitive receptor binding assays. Unlike loose powders from generic suppliers, our alpha-PHP pellets maintain integrity during transit, as validated by accelerated stability testing. A 2023 ACS Chemical Neuroscience study underscores A-PHP’s role in DAT reuptake inhibition research, where Nova Chemics’ consistent dosing supports precise IC50 determinations (DAT Ki ≈ 10-30 nM).
A-PHP Pellets for Forensic and Analytical Research
Forensic laboratories and toxicology centers rely on our A-PHP pellets as certified reference material for:
- Method development and validation (LC-MS/MS, GC-MS) in biological matrices like urine and blood
- Identification of designer cathinones in seized samples, per EMCDDA and UNODC guidelines
- Calibration of NPS screening panels, with A-PHP detection rates rising 15% in 2024 EU reports
- Metabolite profiling, identifying key phase I/II transformations: ω-oxidation, hydroxylation, and pyrrolidine ring cleavage
A 2021 International Journal of Molecular Sciences study on human hepatocyte incubations revealed 12 major metabolites for α-PHP, including carboxy and hydroxy variants—our pellets provide the baseline standard for LODs <0.05 ng/mL. Bulk pellet orders suit high-throughput forensic labs, streamlining workflows without compromising accuracy.
A-PHP in Neuropharmacology and Receptor Binding Studies
Neuroscientists use high-purity A-PHP pellets to investigate:
- Potent NDRI activity (DAT Ki ≈ 20 nM, NET Ki ≈ 150 nM; >50-fold DAT selectivity over SERT)
- SAR within pyrrolidinophenones, comparing alkyl chain lengths (α-PHP vs. α-PVP, α-PPP)
- Stimulant-induced behaviors in rodent models, including hyperlocomotion (ED50: 2.5 mg/kg IP) and reduced brain reward thresholds
- Therapeutic analog development for NDRI-based treatments in ADHD and cognitive enhancement
In a 2021 Drug and Alcohol Dependence study, female rats administered α-PHP via inhalation showed dose-dependent locomotor increases (up to 300% baseline at 1 mg/kg), with pellets offering controlled vaporization for such models. Preclinical data indicate lower hyperthermia risk than α-PVP (ΔT <1.5°C at 3 mg/kg), highlighting A-PHP’s nuanced profile. Nova Chemics’ pellets facilitate exact microdosing in synaptosomal uptake assays, advancing insights into abuse liability.
| Key Pharmacological Properties of A-PHP | Value/Description |
|---|---|
| Transporter Inhibition | Potent NDRI; DAT Ki ≈ 20 nM, NET Ki ≈ 150 nM, SERT Ki >1,000 nM |
| Route of Administration (Research Models) | Oral, IP, inhalation; onset 5-15 min, duration 2-4 hours |
| In Vivo Effects (Rats) | Locomotor ED50: 2.5 mg/kg; suppressed wheel-running at ≥1 mg/kg |
| Metabolic Pathways | ω-Oxidation, hydroxylation (4′-position), N-dealkylation, glucuronidation |
| Toxicity Profile | Cardiovascular strain in high-dose models; limited human data |
| Comparative Potency | 1.5-2x DAT potency over α-PVP; shorter duration |
Quality Assurance – Why Our A-PHP Pellets Are Laboratory Trusted
Every batch of A-PHP pellets undergoes independent third-party analysis. We provide comprehensive reports including NMR spectra (pyrrolidine CH2 at 1.8-2.2 ppm), FTIR (C=O at ~1680 cm⁻¹), HPLC purity (>98%), and uniform pellet weight variation (<2%). When you order A-PHP pellets from Nova Chemics, you receive material exceeding academic standards, often surpassing competitors’ 95-97% thresholds. Our EU facility complies with REACH and GHS, with full traceability from synthesis to pressing—essential for grant-funded research.
Safe & Discreet Worldwide Shipping for A-PHP Pellets
We ship all orders in unmarked, tamper-evident packaging with full tracking. Most customers receive their A-PHP pellets within 3–7 business days (subject to local regulations). Secure SSL checkout supports crypto, bank transfer, and credit for confidentiality. As a Schedule I analog in the US and EU (post-2017 controls), A-PHP is strictly for research; we include export docs affirming lab use only, navigating analog acts seamlessly.
Proper Storage and Handling of A-PHP Pellets
Store A-PHP pellets in a cool, dry place below 25°C (ideally -20°C long-term), shielded from light and humidity to avert oxidation. Use desiccated, airtight vials for stability—shelf life surpasses 18 months. Handle in fume hoods with PPE (nitrile gloves, safety goggles) to avoid dermal exposure. Included SDS details GHS hazards (H301: toxic if swallowed) and spill protocols. For assays, pellets disintegrate rapidly in solvents, prioritizing anhydrous media to preserve activity.
Bulk A-PHP Pellets Orders and Wholesale Pricing
Research institutions and analytical labs benefit from tiered wholesale pricing on A-PHP pellets, with dedicated support for custom pressing (e.g., 10mg/20mg variants). Contact sales for quotes on 100-pellet packs, 500-pellet tubs, or kilogram-equivalent bulk. Discounts begin at 20% for 500+ pellets, with low MOQs for emerging labs. Our supply chain guarantees uninterrupted access for ongoing NPS surveillance programs.
| Bulk Pricing Tiers for A-PHP Pellets (Per Pellet) | Quantity | Price (EUR) |
|---|---|---|
| Small Scale | 10-50 pellets | €1.50 |
| Research Standard | 100-250 pellets | €1.20 |
| Institutional Bulk | 500-1,000 pellets | €0.90 |
| Wholesale Large | 5,000+ pellets | €0.70 (Custom Quote) |
*Prices exclude shipping; ≥98% purity across tiers. Loyalty perks for repeat A-PHP buyers.
Frequently Asked Questions About Buying A-PHP Pellets
Is A-PHP legal to purchase for research?
Yes—exclusively for laboratory/forensic use (not human consumption). Confirm local controls, as it’s analog-scheduled in many areas.
What payment methods do you accept?
Crypto (BTC/ETH), bank transfer, and vetted traditional options for secure buys.
How quickly can I receive my A-PHP pellets order?
EU: 1–3 days | Worldwide: 3–7 days (tracked, plain packaging).
Do you offer other A-PHP formats like powder?
Yes—pellets, crystals, and powder available; all match purity specs—select at checkout.
What differentiates Nova Chemics from other A-PHP suppliers?
Our >98% verified purity, pellet uniformity, and research-centric CoAs outpace rivals like Chems Connect or Explore Chems, often limited to 97% and lacking dosing precision.
Ready to Order A-PHP Pellets Today?
Add your pellet quantity to cart and secure checkout in moments. New buyers get a 5% welcome discount; loyal customers access priority shipping and volume perks. Pair with analogs like α-PiHP for robust cathinone libraries—Nova Chemics curates the premier pyrrolidinophenone selection.
Nova Chemics – Europe’s premier source for research-grade A-PHP pellets and elite cathinones. Order now and advance your investigations with verified excellence.
| Weight | N/A |
|---|---|
| Quantity |
5x180mg ,10x180mg ,20x180mg ,40x180mg ,80x180mg ,160x180mg |

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