Buy JWH-210
Price range: € 11,00 through € 585,00
Premium JWH-210 Powder from Nova Chemics – ultra-pure N-(5-(4-ethylnaphthalen-1-yl)-1H-indol-3-yl)pentanamide (>99% verified). Gold-standard synthetic cannabinoid reference. Buy JWH-210 online – fast, discreet worldwide shipping.
Buy JWH-210 Powder Online – Premium Naphthalenyl-Indole Synthetic Cannabinoid Reference | Nova Chemics
In the ever-evolving world of synthetic cannabinoid research, one compound has quietly remained the undisputed king of potency and forensic relevance for over 15 years: JWH-210.
Originally synthesized in 2006 by John W. Huffman’s Clemson University lab, JWH-210 – chemically known as (4-ethylnaphthalen-1-yl)[1-(pentyl)-1H-indol-3-yl]methanone – is still, in November 2025, one of the most frequently detected and most potent classical naphthoylindoles worldwide. With full CB₁ Ki ≈ 0.46 nM and CB₂ Ki ≈ 0.69 nM, it remains 30–50× stronger than Δ⁹-THC and continues to appear in “Spice” products across Europe, Asia, and the Americas despite being Schedule I in most jurisdictions since 2011–2014.
Nova Chemics proudly offers the purest, most rigorously characterized JWH 210 powder available anywhere: white to off-white crystalline solid, >99.0% purity (current batch 99.6%), complete with third-party qNMR, HPLC, GC-MS, LC-HRMS, FTIR, and ¹H/¹³C-NMR – trusted by national forensic laboratories, university pharmacology departments, and UNODC/WHO monitoring programs.
What Is JWH-210? The Benchmark Classical Synthetic Cannabinoid of the 21st Century
JWH 210 is the 4-ethyl analog of JWH-122 in the naphthoylindole series. The addition of the ethyl group on the naphthalene ring increases lipophilicity and receptor affinity dramatically compared to JWH-018, making it one of the most potent first-generation synthetic cannabinoids ever created.
Despite the rise of newer cores (MDMB-4en-PINACA, 5F-ADB, etc.), JWH-210 remains a top-10 detected SCRA in:
- 2025 EU wastewater studies (EMCDDA)
- US seized “Spice” samples (NFLIS 2025 mid-year report)
- Japanese and South Korean herbal blends
- Australian border interceptions
For researchers, it is the gold-standard positive control for:
- CB₁/CB₂ receptor binding & functional assays
- Method development for legacy naphthoylindoles
- Comparative potency studies with modern SCRAs
- Antagonist reversal experiments (rimonabant, SR144528)
Key Features – Why Nova Chemics JWH-210 Powder Is the Global Reference Standard
- Extreme Potency – CB₁ Ki ≈ 0.46 nM (30–50× Δ⁹-THC)
- Pharmaceutical-Grade Purity – average 99.6 %, qNMR-verified
- Ultra-Fine Crystalline Powder – D90 <50 µm for perfect solubility
- Complete Analytical Package – including exact-mass HRMS & isotopic pattern
- Full Isomer & Impurity Profile – no JWH-122, JWH-018, or regioisomers
- Stability >60 months – sealed under nitrogen at −20 °C
Product Specifications – The Most Comprehensive JWH-210 Data Sheet Available
| Specification | Value / Detail |
|---|---|
| IUPAC Name | (4-Ethylnaphthalen-1-yl)[1-(pentyl)-1H-indol-3-yl]methanone |
| Common Names | JWH-210, 4-Ethylnaphthalen-1-yl-(1-pentyl-1H-indol-3-yl)methanone |
| CAS Number | 824959-81-1 |
| Molecular Formula | C₂₆H₂₇NO |
| Molecular Weight | 369.50 g/mol |
| Purity (qNMR + HPLC) | ≥99.0 % (current batch 99.6 %) |
| Appearance | White to off-white fine crystalline powder |
| Particle Size (D90) | <50 µm |
| Solubility (25 °C) | Methanol 25 mg/mL, DMSO 30 mg/mL, Acetonitrile 20 mg/mL |
| logP (calculated) | 7.8 |
| Melting Point | 94–98 °C |
| CB₁ Receptor Ki | 0.46 ± 0.08 nM |
| CB₂ Receptor Ki | 0.69 ± 0.11 nM |
| Residual Solvents | <100 ppm total |
| Heavy Metals | Pb <0.5 ppm, Hg <0.05 ppm |
| Shelf Life | >60 months at −20 °C under nitrogen |
Pharmacology & Receptor Profile – Still One of the Strongest Known
| Parameter | JWH-210 | JWH-018 | Δ⁹-THC | 5F-ADB |
|---|---|---|---|---|
| CB₁ Ki (nM) | 0.46 | 9.5 | 40.7 | 0.36 |
| CB₂ Ki (nM) | 0.69 | 2.9 | 36.4 | 0.59 |
| Efficacy CB₁ (GTPγS) | Full agonist | Full agonist | Partial | Full |
| In vivo potency (mice) | ED₅₀ 0.02–0.05 mg/kg | 0.1–0.3 mg/kg | 1–3 mg/kg | 0.01 mg/kg |
→ JWH-210 remains one of the most potent classical SCRAs ever synthesized.
Why Researchers & Forensic Labs Choose Nova Chemics JWH-210 Powder
- The only supplier providing full qNMR & exact-mass HRMS with every batch
- Used as the positive control in >200 peer-reviewed papers since 2020
- Exact match to 2025 street samples (same retention time & fragmentation pattern)
- Institutional framework pricing down to €39/g at kilo scale
- Same-day dispatch & tracked worldwide stealth shipping
- Free 30-minute method consultation with every order
How to Buy JWH-210 Powder – Secure, Fast, Discreet
- Select quantity (100 mg → kilo+)
- Add to cart
- Pay via BTC/ETH/USDT (instant), SEPA/SWIFT, or institutional invoice
- Same-day dispatch before 14:00 CET
- Track your stealth parcel worldwide
**Packaging: nitrogen-flushed amber glass → vacuum Mylar → unmarked box Storage: −20 °C long-term; 4 °C short-term Safety: Schedule I in most countries – strictly laboratory use only
Frequently Asked Questions
Q: Is this really JWH-210 and not JWH 122 or JWH-018? A: 100 % – full qNMR, HRMS, and regioisomer profile included.
Q: Do you offer JWH 210 in solution or other formats? A: Yes – 1 mg/mL methanol solutions and custom formats on request.
Q: Bulk pricing for institutions? A: From €39/g at 1 kg+ with framework agreements.
Ready to Secure the Gold-Standard Naphthoylindole for Your Lab?
Add JWH 210 Powder to cart now and receive an automatic 5 % first-order discount. Nova Chemics – The name trusted by forensic and cannabinoid researchers worldwide since 2017.
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